From: David V. Loewe, Jr on 9 Jun 2010 17:35 On Thu, 08 Apr 2010 11:00:37 -0500, "David Loewe, Jr." <dloewe(a)mindspring.com> wrote: >On Thu, 25 Mar 2010 09:08:04 -0400, "CardsFan" <me(a)here.com> wrote: >>"David V. Loewe, Jr" <daveloewe(a)charter.net> wrote >>> On Fri, 5 Mar 2010 04:17:55 -0800 (PST), Tom <drsoong(a)aol.com> wrote: >>>>On Mar 5, 12:08 am, Jeanne Douglas <hlwd...(a)NOSPAMpacbell.net> wrote: >>>>> Tom <drso...(a)aol.com> wrote: >>>>> > Roy and Ahti have run off most of the knowledgeable and fun posters. >>>>> > The only ones who are left are you, Earl and me! lol >>>>> >>>>> Ahem! >>>>> >>>>> > I do enjoy seeing posts from Fred, Karl, DG and Dima. That pretty much >>>>> > covers roll call! >>> >>>>Sorry, Jeanne! I haven't seen anything from you in quite some time and >>>>thought you had gone the way of The Lance. >>>> >>>>It's always a pleasure to hear from you! >>>> >>>>Thanks for the slap in the head! >>> >>> I hardly ever see anyone post anything here worth discussing. >> >>I'm glad to see you're still around. > >Unfortunately, due to the actions of certain posters driving out most >normal conversation, I only look in here sporadically (as you can tell >from the delay in answering your inquiry). > >>How's the health stuff going? > >Where to begin? > >As you may remember, I have inoperable metastatic neuroendocrine >pancreatic tumors in my liver [1]. I got into a clinical trial here at >the Siteman Cancer Center in the Center For Advanced Medicine at >Barnes-Jewish Hospital in town. I was put on the drug Sutent [2], a >renal cancer drug that has some promise in the treatment of other >tumors. The drug worked rather well for a while, but has begun to lose >effectiveness. I am currently on what promises to be my last round or >cycle of Sutent (as the effectiveness should decrease to the point where >I am no longer eligible for the study on the next scan) which will end >May 12th. After that, I'm looking at three primary options - > >1) Percutaneous hepatic perfusion >http://en.wikipedia.org/wiki/Percutaneous_hepatic_perfusion which is >being run as a Phase II Clinical Trial at NHI in Bethesda MD. >http://en.wikipedia.org/wiki/Delcath_Systems,_Inc. >http://en.wikipedia.org/wiki/National_Institutes_of_Health >http://en.wikipedia.org/wiki/National_Cancer_Institute >http://www.msnbc.msn.com/id/29960694 >I still need an MRI of my head and abdomen to be submitted to NIH/NCI. >However, I have some metal in there that was placed to stabilize a >fracture of the right orbital A review of my scans has ruled this out for me in terms of the trial. >2) Hepatic Arterial Chemoembolization >http://en.wikipedia.org/wiki/Neuroendocrine_tumor#Hepatic_artery-delivered_therapies >which would be done at the Mallinkrodt Institute on the south campus at >Barnes-Jewish. > >3) A liver transplant which I don't think my coverage will pay for. I am flying out Sunday to check on option 4) a Phase 1 Trial of the combination of Avastin [1] and Sprycel [2] being done at the NIH/NCI in Bethesda. [3] Other options that opened up include a trial being done at Siteman with Rad001. [4] >In other news, my apartment where I have lived for some 7 years has >recently been determined to, by location (the building basement), >violate St. Louis County's Building Codes. There is no remedy. It has >been condemned and I have to move. The eviction order technically took >effect March 16th. However, as this is not my fault and I have >co-operated with the County, they are giving me leeway. I recently, >with help from the county, obtained assistance from Catholic Charities >of St. Louis and found an apartment. A deposit has been made and first >month's rent paid as well. Current plans are to sign the lease on April >14 and complete the move by the end of day on April 17th. I'll probably >be offline from early Saturday until at least Monday. I'm hoping to get >U-Verse at the new apartment. It seems I can get more TV channels, a >better DVR than I currently have and the same Internet speed for less >than what I pay Charter now (U-Verse is *not* available at my soon to be >old location) - *if* U-Verse is available there (AT&T is supposed to be >checking). > >[1] The pancreatic tumors having long been surgically removed - along >with part of the pancreas (making me an instant diabetic), the spleen >and the gall bladder. > >[2] http://en.wikipedia.org/wiki/Sunitinib >http://en.wikipedia.org/wiki/Sunitinib#Other_solid_tumors [1] http://en.wikipedia.org/wiki/Bevacizumab [2] http://en.wikipedia.org/wiki/Dasatinib [3] http://bethesdatrials.cancer.gov/clinical-research/faq.aspx?ProtocolID=NCI-09-C-0019 [4] http://en.wikipedia.org/wiki/Everolimus -- "So we cheated and we lied and we tested And we never failed to fail it was the easiest thing to do" - Stills, Curtis & Curtis
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